Grey’s Anatomy Season 22 Episode 5 release date and time are not too far away, and fans are excited to find out when they can tune in. In the upcoming episode, titled “Sometimes I Feel Like a Motherless Child,” viewers will get a chance to explore how Jo manages a complex case involving a pregnant patient. Meanwhile, Blue and Jules attend to a diabetic patient, and Simone faces a case that leads to an unexpected revelation.

So, without any further ado, let’s quickly dive right into the release date and time details of Grey’s Anatomy Season 22 Episode 5, along with information on how to watch the show online.

When is the Grey’s Anatomy Season 22 Episode 5 release date & time?

The episode’s release date is Thursday, November 06, 2025, and its release time is 7 p.m. PT and 10 p.m. ET.

Check out its release times in the U.S. below:

Timezone	Release Date	Release Time
Eastern Time	November 06, 2025	10 p.m.
Pacific Time	November 06, 2025	7 p.m.

Find out how many episodes will be available to watch in Grey’s Anatomy Season 22.

Where to watch Grey’s Anatomy Season 22 Episode 5

You can watch Grey’s Anatomy Season 22 Episode 5 via ABC Networks and Hulu.

ABC Network is a prominent American television network, renowned for its diverse array of popular programs, news broadcasts, and live events. Conversely, Hulu is acknowledged as a leading streaming service that offers on-demand access to television shows, films, and exclusive original programming. Both platforms allow audiences to indulge in their beloved long-running drama series, Grey’s Anatomy Season 22.

What is Grey’s Anatomy about?

The official synopsis for Grey’s Anatomy is as follows:

“Follows the personal and professional lives of a group of doctors at Seattle’s Grey Sloan Memorial Hospital.”