Spoiler alert: The following contains details from the Season 22 premiere of “Grey’s Anatomy.”

Longtime “Grey’s Anatomy” fans know that no one is ever safe at Grey Sloan Memorial Hospital.

ABC’s medical drama returned for Season 22 Thursday night, Oct. 9, with a chaotic episode showcasing the aftermath of last season’s hospital explosion.

The blast, caused by a cauterization tool igniting gas in an operating room, injured multiple characters on the show, including Dr. Atticus Lincoln (Chris Carmack). Known as the goofball Link on the show, the orthopedic surgeon was the most severely injured character and shared an emotional farewell phone call with his new wife, Dr. Jo Wilson (Camilla Luddington).

While one fatality was confirmed at the start of the premiere, viewers bore witness to a far more shocking death by the episode’s end. Here’s what happened on the Season 22 premiere.

Does Link die on ‘Grey’s Anatomy’?

No, Dr. Atticus Lincoln managed to survive injuries sustained from the hospital blast thanks to a miraculous recovery and treatment from fellow doctors Owen Hunt (Kevin McKidd), Winston Ndugu (Anthony Hill), Teddy Altman (Kim Raver) and Miranda Bailey (Chandra Wilson).

The majority of the episode left fans worried for the orthopedic surgeon, who was introduced back in Season 15. However, he is expected to recover from his injuries, bringing relief to both Jo and ex-girlfriend Amelia Shepherd (Caterina Scorsone), who shares a child with him.

Who died on ‘Grey’s Anatomy’?

Unfortunately, Dr. Monica Beltran (Natalie Morales) didn’t make it past the new season premiere.

What initially appeared to be just a shattered pelvis turned into a heartbreaking and unexpected death. The pediatric surgeon guided second-year resident Dr. Jules Millin (Adelaide Kane) through a difficult solo procedure on a child.

However, Beltran was trapped under operating light equipment that prevented her from performing the surgery and from being medically examined herself. By the time the fire crew entered the room, Milin completed the surgery, but Beltran had passed away.

Morales joined “Grey’s Anatomy” as a guest star in Season 20 before returning as a recurring actor in Season 21.

Did Grey Sloan Memorial Hospital blow up?

An explosion at Grey Sloan Memorial Hospital left multiple people injured and caused severe damage to the structure, but the hospital remains intact and is set to rebuild.

How many episodes will ‘Grey’s Anatomy’ Season 22 have?

Season 22 of “Grey’s Anatomy” will have 18 episodes, an ABC spokesperson confirmed to USA TODAY.

The season will also include a big milestone: the second episode of the season, “We Built This City,” will be the show’s 450th episode.

Will Meredith Grey return to ‘Grey’s Anatomy’ Season 22?

Yes, Ellen Pompeo has reprised her role as Dr. Meredith Grey in Season 22, with a prominent presence in the premiere. Grey helps save the life of a new surgical intern played by Jade Petty.

Showrunner Meg Marinis told TV Insider that Meredith will spend more hours in the hospital’s operating room.

‘Grey’s Anatomy’ Season 22 cast

Cast members for Season 22 of “Grey’s Anatomy” include:

• Ellen Pompeo as Dr. Meredith Grey
• Chandra Wilson as Miranda Bailey
• James Pickens Jr. as Richard Webber
• Kevin McKidd as Owen Hunt
• Kim Raver as Teddy Altman
• Camilla Luddington as Jo Wilson
• Caterina Scorsone as Amelia Shepherd
• Jason George as Ben Warren
• Chris Carmack as Atticus “Link” Lincoln
• Scott Speedman as Nick Marsh
• Anthony Hill as Winston Ndugu
• Niko Terho as Lucas Adams
• Alexis Floyd as Simone Griffith
• Harry Shum Jr. as Benson Kwan
• Adelaide Kane as Jules Millin